NCSRT OPTISEP Filter Modules

OPTISEP^® SmartFlow™ Tangential Flow

Filtration (SF-TFF)
Biopharm
Filter Modules

NCSRT, Inc. offers a complete line of patented OPTISEP filter modules for biopharmaceutical processing. These include the highly efficient OPTISEP 200, OPTISEP 400, OPTISEP 800, OPTISEP 3000, OPTISEP 7000, and OPTISEP 11000. NCSRT's flat sheet filter modules are available in a wide range of membrane materials and pore sizes to accommodate ultra filtration, microfiltration, nanofiltration, and reverse osmosis processes.

The NCSRT performance advantage comes from the patented OPTISEP SmartFlow Tangential Flow Filtration (SF-TFF) line. The SmartFlow technology in OPTISEP modules creates unique flow channels that reduce gel layer buildup and prevent fouling. This improvement in fluid dynamics optimizes membrane use and expands the performance limits of traditional Tangential Flow Filtration (TFF).

Patented NCSRT SmartFlow Tangential Flow (SF-TFF) technology assures
unprecedented product purity and maximum permeate rates.
Superior fluid dynamics of SmartFlow channels create uniform process conditions
reducing gel layer buildup and preventing fouling.
Uniform flow equals validatable cleaning.
Design enables cost efficient, reliable scale-up performance and decreased processing times.
Provide protein recoveries >99%
Cell mass concentration to >80% solids (wet weight)
Protein concentrations to >40%

The following chart summarizes each filter type:

Membrane Chemistry Review

OPTISEP 200	Flat sheet membrane holder	Laboratory
OPTISEP 400	Flat sheet membrane holder	Laboratory
OPTISEP 800	Flat sheet, stackable membrane holder	Laboratory
OPTISEP 3000	Filter module, 1-2 ft² (0.09-0.19 m²)*	Laboratory/Pilot
OPTISEP 7000	Filter module, 5-20 ft² (0.46-1.86 m²)*	Pilot/Production
OPTISEP 11000	Filter module, 10-100 ft² (0.93-23.23 m²)*	Production

*Note: Multiple filter modules may be stacked in one manifold for larger areas.

Home / About NCSRT / Products / Library / News / Contact