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Membrane Chemistry
Material |
Physical Attribute |
Performance Attribute |
Limitations |
Cellulose |
Most neutral membrane very low binding |
Charge has little affect on separation Highest filtration rates (with product) |
No storage in NaOH |
Polyesthersulfone (PES) |
Negatively charged |
Charge can affect separation | Protein passage, variable |
Modified Polysulfone (PS) |
Mix of RC & PES attributes |
Dependent upon specific modification | Dependent upon specific modification |
Polypropylene (PP) |
Positively charged |
Can absorb endotoxins |
Hollow fiber most common Low permeate rate |
Ceramics |
Positively charged |
SIP compatible |
High protein binding Large pumps required |
